Complex Projective Synchronization in Drive-Response Stochastic Complex Networks by Impulsive Pinning Control

The complex projective synchronization in drive-response stochastic coupled networks with complex-variable systems is considered. The impulsive pinning control scheme is adopted to achieve complex projective synchronization and several simple and practical sufficient conditions are obtained in a general drive-response network. In addition, the adaptive feedback algorithms are proposed to adjust the control strength. Several numerical simulations are provided to show the effectiveness and feasibility of the proposed methods

Adsorption of Selenium and Strontium on Goethite: EXAFS Study and Surface Complexation Modeling of the Ternary Systems

Knowledge of the geochemical behavior of selenium and strontium is critical for the safe disposal of radioactive wastes. Goethite, as one of the most thermodynamically stable and commonly occurring natural iron oxy-hydroxides, promisingly retains these elements. This work comprehensively studies the adsorption of Se(IV) and Sr(II) on goethite. Starting from electrokinetic measurements, the binary and ternary adsorption systems are investigated and systematically compared via batch experiments, EXAFS analysis, and CD-MUSIC modeling. Se(IV) forms bidentate inner-sphere surface complexes, while Sr(II) is assumed to form outer-sphere complexes at low and intermediate pH and inner-sphere complexes at high pH. Instead of a direct interaction between Se(IV) and Sr(II), our results indicate an electrostatically driven mutual enhancement of adsorption. Adsorption of Sr(II) is promoted by an average factor of 5 within the typical groundwater pH range from 6 to 8 for the concentration range studied here. However, the interaction between Se(IV) and Sr(II) at the surface is two-sided, Se(IV) promotes Sr(II) outer-sphere adsorption, but competes for inner-sphere adsorption sites at high pH. The complexity of surfaces is highlighted by the inability of adsorption models to predict isoelectric points without additional constraints

Combination analysis of genome-wide association and transcriptome sequencing of residual feed intake in quality chickens

GO mapping for genes within the 50 bp flanking regions of the significant RFI-related SNPs. (XLS 31 kb

Evaluation of three high abundance protein depletion kits for umbilical cord serum proteomics

<p>Abstract</p> <p>Background</p> <p>High abundance protein depletion is a major challenge in the study of serum/plasma proteomics. Prior to this study, most commercially available kits for depletion of highly abundant proteins had only been tested and evaluated in adult serum/plasma, while the depletion efficiency on umbilical cord serum/plasma had not been clarified. Structural differences between some adult and fetal proteins (such as albumin) make it likely that depletion approaches for adult and umbilical cord serum/plasma will be variable. Therefore, the primary purposes of the present study are to investigate the efficiencies of several commonly-used commercial kits during high abundance protein depletion from umbilical cord serum and to determine which kit yields the most effective and reproducible results for further proteomics research on umbilical cord serum.</p> <p>Results</p> <p>The immunoaffinity based kits (PROTIA-Sigma and 5185-Agilent) displayed higher depletion efficiency than the immobilized dye based kit (PROTBA-Sigma) in umbilical cord serum samples. Both the PROTIA-Sigma and 5185-Agilent kit maintained high depletion efficiency when used three consecutive times. Depletion by the PROTIA-Sigma Kit improved 2DE gel quality by reducing smeared bands produced by the presence of high abundance proteins and increasing the intensity of other protein spots. During image analysis using the identical detection parameters, 411 ± 18 spots were detected in crude serum gels, while 757 ± 43 spots were detected in depleted serum gels. Eight spots unique to depleted serum gels were identified by MALDI- TOF/TOF MS, seven of which were low abundance proteins.</p> <p>Conclusions</p> <p>The immunoaffinity based kits exceeded the immobilized dye based kit in high abundance protein depletion of umbilical cord serum samples and dramatically improved 2DE gel quality for detection of trace biomarkers.</p

Single-cell mapping of N6-methyladenosine in esophageal squamous cell carcinoma and exploration of the risk model for immune infiltration

BackgroundN6-methyladenosine (m6A) modification is the most common RNA modification, but its potential role in the development of esophageal cancer and its specific mechanisms still need to be further investigated.MethodsBulk RNA-seq of 174 patients with esophageal squamous carcinoma from the TCGA-ESCC cohort, GSE53625, and single-cell sequencing data from patients with esophageal squamous carcinoma from GSE188900 were included in this study. Single-cell analysis of scRNA-seq data from GSE188900 of 4 esophageal squamous carcinoma samples and calculation of PROGENy scores. Demonstrate the scoring of tumor-associated pathways for different cell populations. Cell Chat was calculated for cell populations. thereafter, m6A-related differential genes were sought and risk models were constructed to analyze the relevant biological functions and impact pathways of potential m6A genes and their impact on immune infiltration and tumor treatment sensitivity in ESCC was investigated.ResultsBy umap downscaling analysis, ESCC single-cell data were labelled into clusters of seven immune cell classes. Cellchat analysis showed that the network interactions of four signaling pathways, MIF, AFF, FN1 and CD99, all showed different cell type interactions. The prognostic risk model constructed by screening for m6A-related differential genes was of significant value in the prognostic stratification of ESCC patients and had a significant impact on immune infiltration and chemotherapy sensitivity in ESCC patients.ConclusionIn our study, we explored a blueprint for the distribution of single cells in ESCC based on m6A methylation and constructed a risk model for immune infiltration analysis and tumor efficacy stratification in ESCC on this basis. This may provide important potential guidance for revealing the role of m6A in immune escape and treatment resistance in esophageal cancer

The Extent, Nature, and Origin of K and Rb Depletions and Isotopic Fractionations in Earth, the Moon, and Other Planetary Bodies

Moderately volatile elements (MVEs) are depleted and isotopically fractionated in the Moon relative to Earth. To understand how the composition of the Moon was established, we calculate the equilibrium and kinetic isotopic fractionation factors associated with evaporation and condensation processes. We also reassess the levels of depletions of K and Rb in planetary bodies. Highly incompatible element ratios are often assumed to be minimally affected by magmatic processes, but we show that this view is not fully warranted, and we develop approaches to mitigate this issue. The K/U weight ratios of Earth and the Moon are estimated to be 9704 and 2448, respectively. The 87Rb/86Sr atomic ratios of Earth and the Moon are estimated to be 0.072 5 and 0.015 4, respectively. We show that the depletions and heavy isotopic compositions of most MVEs in the Moon are best explained by evaporation in 99%-saturated vapor. At 99% saturation in the protolunar disk, Na and K would have been depleted to levels like those encountered in the Moon on timescales of ∼40–400 days at 3500–4500 K, which agrees with model expectations. In contrast, at the same saturation but a temperature of 1600–1800 K relevant to hydrodynamic escape from the lunar magma ocean, Na and K depletions would have taken 0.1–103 Myr, which far exceeds the 1000 yr time span until plagioclase flotation hinders evaporation from the magma ocean. We conclude that the protolunar disk is a much more likely setting for the depletion of MVEs than the lunar magma ocean

Effect of Kang Fu Yan capsule on phenol mucilage-induced intrauterine adhesion injury in female rats

Purpose: To investigate the effect of Kang fu yan capsule (KFYC) on phenol mucilage-induced intrauterine adhesion (IUA) in a rat model, and the underlying mechanisms. Methods: An IUA model was established by injecting 0.06 mL of 25 % phenol mucilage into the uterus of female Sprague-Dawley rats. The IUA model rats (n=59) were randomly divided into 5 groups: IUA group, fuke qianjin tablet group (FKQJT, 0.22 mg/kg), and 3 KFYC groups given different doses of the drug i.e. 0.13, 0.39and 1.17 mg/kg. A group of 10 healthy female rats served as control. After 19 days treatment, blood samples were collected for determination of IL-2 and IL-10 by ELISA, while uterine tissues were subjected to histological examination using hematoxylin and eosin staining (H&amp;E) and Masson staining. Expressions of Notch1, recombination signal binding protein-JK (RBP-JK), a disintegrin and metalloprotease (ADAM)-12, ADAM-15, matrix metalloprotein-9 (MMP-9), and inhibitor of NF-κB (IĸB) in uterine tissues were determined using RT-qPCR and western blot analysis. Results: Compared to IUA group, histological results showed reduced inflammatory cell infiltration in rat uterine tissue of KFYC group. Moreover, KFYC significantly reversed uterine fibrosis (p &lt; 0.05). Serum concentrations of IL-2 significantly decreased in KFYC groups (p &lt; 0.05 or p &lt; 0.01), and there was significant increases the serum concentrations of IL-10 in KFYC groups (p &lt; 0.05 or &lt; 0.01), when compared to IUA group. The mRNA and protein expressions of Notch1, RBP-JK, ADAM-12, ADAM-15, MMP-9 were also significantly down-regulated (p &lt; 0.05), while protein expression of IĸB was upregulated in KFYC group, when compared to IUA group. Conclusion: KFYC exerts an anti-IUA effect via amelioration of uterine inflammation and fibrosis, probably via a mechanism involving regulation of Notch1/ADAM pathway

Self-organized pattern formation of an atmospheric pressure plasma jet in a dielectric barrier discharge configuration

This letter reports the observation of self-organized patterns formed in a 29 mm wide atmospheric pressure plasma jet. By altering the gas flow rate and/or the applied voltage, the plasma jet is seen to have at least three different modes, namely, a diffuse-looking discharge, a self-organized discharge, and an unstable discharge with randomly occurring plasma channels. The self-organized discharge mode is characterized by several bright plasma channels embedded in a diffuse and dim plasma background. These plasma channels are regularly spaced from each other and their self-organized patterns are shown to evolve abruptly